Leucine-rich repeat (LRR) database and LRRfinder tool from the Royal Veterinary College (RVC)

Molecular Immunology Research Group
Royal Veterinary College

The Molecular Immunology Research Group, headed by Prof. Dirk Werling, is part of the Pathology and Infectious Diseases department of the Royal Veterinary College, Hawkshead Campus.

Our main objectives are:

For more information please visit our website.

Bioinformatics within Molecular Immunology

The group utilizes Bioinformatics to develop and implement software to support our research goals here at the RVC. Currently, our main bioinformatic focus is BioChip, a UK effort to develop and validate(where possible) a generic platform technology and series of protocols for the identification and characterisation of viruses responsible for diseases in animals, plants and fish, including the major quarantine viruses of interest to Defra. Bioinformatics is a key element in microarray data analysis and here at the RVC we aim to not only analyse data but to produce tools which will facilitate faster, more efficient data throughput.

Additionally, we have experience in Protein Modelling using existing software packages and developing our own algorithms. Insights into the 3D structure of a protein are of great assistance in understanding protein function and experimental planning. Vast quantities of protein sequence data is generated by high throughput DNA sequencing efforts and it is the role of Protein Modelling to provide a much quicker overiew of protein structure than relatively expensive and time-comsuming X-ray crystallography or NMR spectroscapy.

Finally, with our Bioinformatic Resource we hope to provide the scientific community with a range of tools to facilitate data analysis across a broad spectrum of research areas.